A signaling pathway map of plasminogen activator inhibitor-1 (PAI-1/SERPINE-1): a review of an innovative frontier in molecular aging and cellular senescence

Abstract Plasminogen activator inhibitor-1 (PAI-1) is a vital regulator of the fibrinolytic mechanism and has been intricately involved in various physiological and clinical processes, including cancer, thrombosis, and wound healing.The PAI-1 signaling pathway is multifaceted, encompassing numerous signaling molecules and nodes.Recent studies have

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The use of Turkic loanwords in the Russian language

The subject of the research is loanwords form Turkic languages in the Russian language.The basic rules for the development of the language, its connections with the history of society in different periods are clearly manifested precisely in the vocabulary.Loanwords from Turkic languages were borrowed through oral speech.This led to the emergence of

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Trema orientale (L.) Blume: A review of its taxonomy, traditional uses, phytochemistry, pharmacological activities and domestication potential

Trema orientale (L.) Blume is an important medicinal plant with multiple applications for treating several disease conditions.This study compiled published data on botanical, traditional uses, phytochemistry, pharmacology, and antimicrobials, coupled with discussing the conservation and domestication potential of T.orientale.Data were sourced from

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